If have anything I can test for you, would be my pleasure.
I've tried this here with Windows 2012 R2 Datacenter at the server, and Microsoft Remote Desktop 8.0.43 on macOS 10.12.6, and everything looks fine for me. Remote Desktop is running at 1600x1000 in 24bit colour.
What exactly are you running on the client and server?
Must be something wrong in my setup: Windows Server 2008 r2 TS, acessing with two Full HD 24" monitors in 32bit color depth., themes disabled, font smoothing enabled, composition enabled, visual effects disabled.
I just can't read texts... They are "faded". See attached screenshot for reference.